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100,000,000 shares authorized; 56,116,243 and 45,241,808 shares issued and outstanding at June 30, 2022 and December 31, 2021, respectively Common Stock, Value, Issued Additional paid-in capital Additional Paid in Capital Purchase in-process research and development technology Cash payment Payments to Acquire in Process Research and Development Statistical Measurement [Domain] Statistical Measurement [Domain] Exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Exercisable, aggregate intrinsic value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Share-based Payment Arrangement [Abstract] Share-Based Payment Arrangement [Abstract] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Sales Agreement At the Market Offering Agreement [Member] At the Market Offering Agreement Cash, cash equivalents and restricted cash at beginning of period Cash, cash equivalents and restricted cash at end of period Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents COMMITMENTS AND CONTINGENCIES Commitments and Contingencies Disclosure [Text Block] Current liabilities: Liabilities, Current [Abstract] Common stock, shares issued (in shares) Common Stock, Shares, Issued Net loss Net loss Net Income (Loss) Attributable to Parent Measurement Input Type [Domain] Measurement Input Type [Domain] Warrants exercised for cash (in shares) Stock Issued During Period, Shares, Warrants Exercised Stock Issued During Period, Shares, Warrants Exercised Antidilutive securities excluded from computation of earnings per share (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Prepaid insurance Prepaid Insurance Equity Component [Domain] Equity Component [Domain] Amendment Flag Amendment Flag Consolidation, Less than Wholly Owned Subsidiary, Parent Ownership Interest, Effects of Changes, Net [Table] Consolidation, Less than Wholly Owned Subsidiary, Parent Ownership Interest, Effects of Changes, Net [Table] Net cash used in investing activities Net Cash Provided by (Used in) Investing Activities Discount rate Measurement Input, Discount Rate [Member] Ownership [Axis] Ownership [Axis] Related Party [Domain] Related Party [Domain] Plan Name [Axis] Plan Name [Axis] Entity Current Reporting Status Entity Current Reporting Status Other assets Other Assets, Noncurrent Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Exercisable (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Expected dividend Measurement Input, Expected Dividend Rate [Member] Wedbush Wedbush Securities Inc. [Member] Wedbush Securities Inc. 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